Improved tumor contrast achieved by single time point dual-reporter fluorescence imaging
نویسندگان
چکیده
منابع مشابه
Improved tumor contrast achieved by single time point dual-reporter fluorescence imaging.
In this study, we demonstrate a method to quantify biomarker expression that uses an exogenous dual-reporter imaging approach to improve tumor signal detection. The uptake of two fluorophores, one nonspecific and one targeted to the epidermal growth factor receptor (EGFR), were imaged at 1 h in three types of xenograft tumors spanning a range of EGFR expression levels (n=6 in each group). Using...
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ژورنال
عنوان ژورنال: Journal of Biomedical Optics
سال: 2012
ISSN: 1083-3668
DOI: 10.1117/1.jbo.17.6.066001